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Copyright (c) 2024 Sameer Bandar Alotaibi, Muteb Mohammed Albalawi, Hamoud Mohammed Albahli, Abdullah Mohammed Nasser Al-Qahtani, Maram Faisal Al-Mutairi, Zaid Obeed Mobark Al-Dawsari, Sameera Shobaq Ali Hakami, Fawziah Tahoos Mubarak Al-Ghamdi, Fahad Khulyf Alenezi, Abdullah Ali Suhaib Alghtane, Haidar Mohammed I Majmi

This work is licensed under a Creative Commons Attribution 4.0 International License.
Integrated Emergency Care Pathways: The Collaborative Roles of Medical Laboratory Scientists, EMS Professionals, Pharmacists, Nurses, and Resident Physicians in Time-Critical Patient Management
Corresponding Author(s) : Sameer Bandar Alotaibi
Saudi Journal of Medicine and Public Health, Vol. 1 No. 2 (2024)
Abstract
Time-critical emergency conditions — including acute ischemic stroke, ST-elevation myocardial infarction (STEMI), sepsis, and major trauma — demand coordinated, rapid responses in which delays of minutes translate into measurable increases in morbidity and mortality. This narrative review synthesizes contemporary evidence (2016–2024) on integrated emergency care pathways and the collaborative roles of medical laboratory scientists, emergency medical services (EMS) professionals, pharmacists, nurses, and resident physicians in time-critical patient management. A systematic literature search was conducted across PubMed, Scopus, and CINAHL databases. Evidence demonstrates that targeted deployment of interprofessional pre-hospital teams significantly reduces mortality risk (AOR 0.80; 95% CI [0.68, 0.91]) and increases survival (AOR 1.49; 95% CI [1.31, 1.69]) compared with paramedic-only care. Point-of-care testing guided by laboratory specialists reduces time to treatment, while emergency pharmacists prevent up to 45% of medication errors and generate substantial cost avoidance. Nurse-led rapid response systems improve rescue success rates from 66.5% to 86.6% and reduce cardiac arrest rates. Structured communication tools such as SBAR significantly enhance team task performance. This review proposes an integrated framework emphasizing parallel processing, shared situational awareness, and interprofessional training to optimize emergency care outcomes.
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- 1. Al Dhefeeri, A. K., Aldhafeeri, A. M. B., Alsharari, G. A. S., Alhazmy, M. S. F., Alomayri, M. I. A., & Alanazi, H. A. M. (2024). The importance of triage in the emergency department. Gland Surgery, 9(2), 285-291.
- 2. Alghamdi, A., Cook, E., Carlton, E., Siriwardena, A., Hann, M., Thompson, A., ... & Body, R. (2019). PRe-hospital Evaluation of Sensitive TrOponin (PRESTO) Study: multicentre prospective diagnostic accuracy study protocol. BMJ Open, 9(10), e032834.
- 3. Al Mansour, N. M. A., Alyami, A. A. B. M., Alyami, M. D. S., Almansour, H. A. S., Almasad, G. R. S., Alyami, A. S. A., & Hirfish, H. H. H. (2022). Is an “Emergency Medicine Pharmacist” Essential?. Advances in Clinical and Experimental Medicine, 9(4).
- 4. Alotaibi, T. M. M., wazi Alqahtani, F., Majrashi, E. B., Alqahtani, F. A. F., Alshammari, A. O. H., Al-Mutairi, N. M. A., ... & Almotiri, S. M. M. (2024). Nursing Practice In Emergency Care Settings: Evidence-Based Approaches. The Review of Diabetic Studies, 253-268.
- 5. Azadi, H., Robinson, G., Barati, A. A., Goli, I., Moghaddam, S. M., Siamian, N., ... & Janečková, K. (2023). Smart land governance: Towards a conceptual framework. Land, 12(3), 600.
- 6. Caretta‐Weyer, H. A., Sebok‐Syer, S. S., Morris, A. M., Schnapp, B. H., Fant, A. L., Scott, K. R., ... & Yarris, L. M. (2024). Better together: a multistakeholder approach to developing specialty‐wide entrustable professional activities in emergency medicine. AEM education and training, 8(2), e10974.
- 7. Chae, S., & Shon, S. (2024). Effectiveness of simulation-based interprofessional education on teamwork and communication skills in neonatal resuscitation. BMC medical education, 24(1), 602.
- 8. Chen, W. C., Chaou, C. H., Ng, C. J., Liu, Y. P., & Chang, Y. C. (2022). Assessing the effectiveness of pediatric emergency medicine education in emergency medicine residency training: A national survey. Hong Kong Journal of Emergency Medicine, 29(6), 349-357.
- 9. Cross, J. L., Backhouse, T., Hammond, S. P., Penhale, B., Scheibl, F., Lambert, N., ... & Poland, F. M. (2024). Disjunctures in practice: ethnographic observations of orthopaedic ward practices in the care of older adults with hip fracture and presumed cognitive impairment. Ageing & Society, 44(8), 1727-1748.
- 10. Duran, H. T., & McIvor, W. (2021). Simulation training for crisis management: Demonstrating impact and value. Advances in Anesthesia, 39, 241-257.
- 11. Escribano, S., Sánchez-Marco, M., Espinosa-Ramírez, S., Mateos-Rodríguez, A., Fernández-Lebrusán, L., & Cabañero-Martínez, M. J. (2024). Emergency crisis resource management: a simulation-based course developed by the Spanish Society of Emergency Medicine (SEMES) for health sciences students. Emergencias: revista de la Sociedad Espanola de Medicina de Emergencias, 36(1), 41-7.
- 12. Giles, A., Prusinski, R., & Wallace, L. (2024). Maternal-newborn nursing. OpenStax.
- 13. Goulas, C., Lohan, L., Laureau, M., Perier, D., Pinzani, V., Faucanie, M., ... & Breuker, C. (2023). Involvement of pharmacists in the emergency department to correct errors in the medication history and the impact on adverse drug event detection. Journal of Clinical Medicine, 12(1), 376.
- 14. Gunderson, M. R., Florin, A., Price, M., & Reed, J. (2020). NEMSMA position statement and white paper: process and outcomes data sharing between EMS and receiving hospitals. Prehospital emergency care, 25(2), 307-313.
- 15. Kelen, G. D., Wolfe, R., D’Onofrio, G., Mills, A. M., Diercks, D., Stern, S. A., ... & Sokolove, P. E. (2021). Emergency department crowding: the canary in the health care system. NEJM Catalyst Innovations in Care Delivery, 2(5).
- 16. Kobayashi, A., Czlonkowska, A., Ford, G. A., Fonseca, A. C., Luijckx, G. J., Korv, J., ... & De Keyser, J. (2018). European Academy of Neurology and European Stroke Organization consensus statement and practical guidance for pre‐hospital management of stroke. European journal of neurology, 25(3), 425-433.
- 17. Kunze-Szikszay, N., Krack, L. A., Wildenauer, P., Wand, S., Heyne, T., Walliser, K., ... & Roessler, M. (2016). The pre-hospital administration of tranexamic acid to patients with multiple injuries and its effects on rotational thrombelastometry: a prospective observational study in pre-hospital emergency medicine. Scandinavian journal of trauma, resuscitation and emergency medicine, 24(1), 122.
- 18. Lamba, S., Nagurka, R., Offin, M., & Scott, S. R. (2015). Structured communication: teaching delivery of difficult news with simulated resuscitations in an Emergency Medicine Clerkship. Western Journal of Emergency Medicine, 16(2), 344.
- 19. Lammers, D., Henry, R., McClellan, J., Armen, S., Koch, E., Sulava, E., ... & Holcomb, J. B. (2023). Prolonged tourniquet use in extremity trauma: What you need to know. Journal of Trauma and Acute Care Surgery, 10-1097.
- 20. Lee, K. R., & Kim, E. J. (2020). Relationship between interprofessional communication and team task performance. Clinical Simulation in Nursing, 43, 44-50.
- 21. Magnusson, C., Herlitz, J., Axelsson, C., Höglind, R., Lökholm, E., Hörnfeldt, T. H., ... & Wennberg, P. (2024). Added predictive value of prehospital measurement of point-of-care lactate in an adult general EMS population in Sweden: a multi-centre observational study. Scandinavian journal of trauma, resuscitation and emergency medicine, 32(1), 72.
- 22. Massey, D., Aitken, L. M., & Chaboyer, W. (2015). The impact of a nurse led rapid response system on adverse, major adverse events and activation of the medical emergency team. Intensive and Critical Care Nursing, 31(2), 83-90.
- 23. Mazzone, E. (2024). Integrating Psma Expression Patterns, Morphological And Clinical Features To Optimize Detection Of Nodal Metastases In Patients Treated With Psma Radio-Guided Robot-Assisted Radical Prostatectomy And Extended Pelvic Lymph Node Dissection.
- 24. Morgan, O., Yarham, E., Hudson, A., & Cole, E. (2021). Do pre-hospital physicians improve mortality in major trauma patients? A systematic review. Trauma, 23(1), 3-12.
- 25. O’Brien, B., Bevan, K., Brockington, C., Murphy, J., & Gilbert, R. (2023). Effects of simulation-based cardiopulmonary and respiratory case training experiences on interprofessional teamwork: a systematic review. Canadian Journal of Respiratory Therapy: CJRT= Revue Canadienne de la Thérapie Respiratoire: RCTR, 59, 85.
- 26. Ortmann, M. J., Johnson, E. G., Jarrell, D. H., Bilhimer, M., Hayes, B. D., Mishler, A., ... & Zimmerman, D. E. (2021). ASHP guidelines on emergency medicine pharmacist services. American Journal of Health-System Pharmacy, 78(3), 261-275.
- 27. Otudi, M. I. A., Alanezi, A. A. F., Alogdi, M. A. A., Alotaibi, N. M. H., Almutairi, M. R., Aloneze, K. A., ... & Alfahadi, F. J. (2024). Optimizing Interprofessional Trauma Care Pathways: A Systematic Review of Workflow Integration from Prehospital Stabilization to Definitive Disposition. Saudi Journal of Medicine and Public Health, 1(2), 1359-1364.
- 28. Öztürk, A., & Demirci, G. (2023). Determining the turnaround time in a newly established biochemistry laboratory. Archives of Current Medical Research, 4(3), 153-177.
- 29. Raymond, J., Parrein, P., Barat, E., Chenailler, C., Decreau-Gaillon, G., Varin, R., & Joly, L. M. (2023, November). Pharmacist tracking and correction of medication errors: an improvement project in the observation ward of the emergency department. In Annales Pharmaceutiques Françaises (Vol. 81, No. 6, pp. 1007-1017). Elsevier Masson.
- 30. Rech, M. A., Adams, W., Smetana, K. S., Gurnani, P. K., Patel, M. A. V. B., Peppard, W. J., ... & Flannery, A. H. (2021). Pharmacist avoidance or reductions in medical costs in patients presenting the emergency department: PHARM-EM study. Critical Care Explorations, 3(4), e0406.
- 31. Rogers, L. M. (2020). Exploring the Role of Medical Scribes on ED Patient Flow and Provider Productivity (Doctoral dissertation, Brandman University).
- 32. Rosen, M. A., DiazGranados, D., Dietz, A. S., Benishek, L. E., Thompson, D., Pronovost, P. J., & Weaver, S. J. (2018). Teamwork in healthcare: Key discoveries enabling safer, high-quality care. American Psychologist, 73(4), 433.
- 33. Samadbeik, M., Staib, A., Boyle, J., Khanna, S., Bosley, E., Bodnar, D., ... & Sullivan, C. (2024). Patient flow in emergency departments: a comprehensive umbrella review of solutions and challenges across the health system. BMC health services research, 24(1), 274.
- 34. Schilling, S., Armaou, M., Morrison, Z., Carding, P., Bricknell, M., & Connelly, V. (2022). Understanding teamwork in rapidly deployed interprofessional teams in intensive and acute care: A systematic review of reviews. Plos one, 17(8), e0272942.
- 35. Schouten, A. M., Flipse, S. M., van Nieuwenhuizen, K. E., Jansen, F. W., van der Eijk, A. C., & van den Dobbelsteen, J. J. (2023). Operating room performance optimization metrics: a systematic review. Journal of Medical Systems, 47(1), 19.
- 36. Seymour, C. W., Liu, V. X., Iwashyna, T. J., Brunkhorst, F. M., Rea, T. D., Scherag, A., ... & Angus, D. C. (2016). Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (Sepsis-3). Jama, 315(8), 762-774.
- 37. Shiell, A., Fry, M., Elliott, D., & Elliott, R. (2022). Exploration of a rapid response team model of care: A descriptive dual methods study. Intensive and Critical Care Nursing, 73, 103294.
- 38. Sirikul, W., Piankusol, C., Wittayachamnankul, B., Riyapan, S., Supasaovapak, J., Wongtanasarasin, W., & McNally, B. (2022). A retrospective multi-centre cohort study: Pre-hospital survival factors of out-of-hospital cardiac arrest (OHCA) patients in Thailand. Resuscitation plus, 9, 100196.
- 39. Sprogis, S. K., Currey, J., Jones, D., & Considine, J. (2021). Use of the pre-medical emergency team tier of rapid response systems: a scoping review. Intensive and Critical Care Nursing, 65, 103041.
- 40. Strandmark, R., Herlitz, J., Axelsson, C., Claesson, A., Bremer, A., Karlsson, T., ... & Ravn-Fischer, A. (2015). Determinants of pre-hospital pharmacological intervention and its association with outcome in acute myocardial infarction. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 23(1), 105.
- 41. Thomas, A., Heraud, F., Gros, S., Allenet, B., & Lesage, P. (2022). Les urgences, carrefour stratégique pour la conciliation médicamenteuse et la pharmacie clinique. Le Pharmacien Clinicien, 57(4), e55.
- 42. Vitale, E., & Cannito, G. (2020). Observational study of the handover with the SBAR method at Bari Polyclinic complex. Professioni Infermieristiche, 73(1), 27-32.
- 43. Waydhas, C., Hermes, C., Kumpf, O., Mutlak, H., Spannagl, M., Walcher, F., & Luppa, P. B. (2024). Position paper of DGKL and DIVI on requirements for laboratory services in intensive care and emergency medicine. Medizinische Klinik, Intensivmedizin und Notfallmedizin, 120(1), 47.
- 44. Weatherburn, D. C. (2023). The role of the intensive care nurse in the medical emergency team: A constructivist grounded theory study. Australian Critical Care, 36(1), 119-126.
- 45. Won, Y. H., & Kang, J. (2022). Development of a comprehensive model for the role of the rapid response team nurse. Intensive and Critical Care Nursing, 68, 103136.
- 46. Wu, Y., Wang, J., Luo, F., Li, D., Ran, X., Ren, X., ... & Wei, J. (2022). Construct and clinical verification of a nurse-led rapid response systems and activation criteria. BMC nursing, 21(1), 311.
- 47. YEMDD. (2024). Is an "Emergency Medicine Pharmacist" essential? Journal of Emergency Medicine and Critical Care, 12(2), 45–52.
References
1. Al Dhefeeri, A. K., Aldhafeeri, A. M. B., Alsharari, G. A. S., Alhazmy, M. S. F., Alomayri, M. I. A., & Alanazi, H. A. M. (2024). The importance of triage in the emergency department. Gland Surgery, 9(2), 285-291.
2. Alghamdi, A., Cook, E., Carlton, E., Siriwardena, A., Hann, M., Thompson, A., ... & Body, R. (2019). PRe-hospital Evaluation of Sensitive TrOponin (PRESTO) Study: multicentre prospective diagnostic accuracy study protocol. BMJ Open, 9(10), e032834.
3. Al Mansour, N. M. A., Alyami, A. A. B. M., Alyami, M. D. S., Almansour, H. A. S., Almasad, G. R. S., Alyami, A. S. A., & Hirfish, H. H. H. (2022). Is an “Emergency Medicine Pharmacist” Essential?. Advances in Clinical and Experimental Medicine, 9(4).
4. Alotaibi, T. M. M., wazi Alqahtani, F., Majrashi, E. B., Alqahtani, F. A. F., Alshammari, A. O. H., Al-Mutairi, N. M. A., ... & Almotiri, S. M. M. (2024). Nursing Practice In Emergency Care Settings: Evidence-Based Approaches. The Review of Diabetic Studies, 253-268.
5. Azadi, H., Robinson, G., Barati, A. A., Goli, I., Moghaddam, S. M., Siamian, N., ... & Janečková, K. (2023). Smart land governance: Towards a conceptual framework. Land, 12(3), 600.
6. Caretta‐Weyer, H. A., Sebok‐Syer, S. S., Morris, A. M., Schnapp, B. H., Fant, A. L., Scott, K. R., ... & Yarris, L. M. (2024). Better together: a multistakeholder approach to developing specialty‐wide entrustable professional activities in emergency medicine. AEM education and training, 8(2), e10974.
7. Chae, S., & Shon, S. (2024). Effectiveness of simulation-based interprofessional education on teamwork and communication skills in neonatal resuscitation. BMC medical education, 24(1), 602.
8. Chen, W. C., Chaou, C. H., Ng, C. J., Liu, Y. P., & Chang, Y. C. (2022). Assessing the effectiveness of pediatric emergency medicine education in emergency medicine residency training: A national survey. Hong Kong Journal of Emergency Medicine, 29(6), 349-357.
9. Cross, J. L., Backhouse, T., Hammond, S. P., Penhale, B., Scheibl, F., Lambert, N., ... & Poland, F. M. (2024). Disjunctures in practice: ethnographic observations of orthopaedic ward practices in the care of older adults with hip fracture and presumed cognitive impairment. Ageing & Society, 44(8), 1727-1748.
10. Duran, H. T., & McIvor, W. (2021). Simulation training for crisis management: Demonstrating impact and value. Advances in Anesthesia, 39, 241-257.
11. Escribano, S., Sánchez-Marco, M., Espinosa-Ramírez, S., Mateos-Rodríguez, A., Fernández-Lebrusán, L., & Cabañero-Martínez, M. J. (2024). Emergency crisis resource management: a simulation-based course developed by the Spanish Society of Emergency Medicine (SEMES) for health sciences students. Emergencias: revista de la Sociedad Espanola de Medicina de Emergencias, 36(1), 41-7.
12. Giles, A., Prusinski, R., & Wallace, L. (2024). Maternal-newborn nursing. OpenStax.
13. Goulas, C., Lohan, L., Laureau, M., Perier, D., Pinzani, V., Faucanie, M., ... & Breuker, C. (2023). Involvement of pharmacists in the emergency department to correct errors in the medication history and the impact on adverse drug event detection. Journal of Clinical Medicine, 12(1), 376.
14. Gunderson, M. R., Florin, A., Price, M., & Reed, J. (2020). NEMSMA position statement and white paper: process and outcomes data sharing between EMS and receiving hospitals. Prehospital emergency care, 25(2), 307-313.
15. Kelen, G. D., Wolfe, R., D’Onofrio, G., Mills, A. M., Diercks, D., Stern, S. A., ... & Sokolove, P. E. (2021). Emergency department crowding: the canary in the health care system. NEJM Catalyst Innovations in Care Delivery, 2(5).
16. Kobayashi, A., Czlonkowska, A., Ford, G. A., Fonseca, A. C., Luijckx, G. J., Korv, J., ... & De Keyser, J. (2018). European Academy of Neurology and European Stroke Organization consensus statement and practical guidance for pre‐hospital management of stroke. European journal of neurology, 25(3), 425-433.
17. Kunze-Szikszay, N., Krack, L. A., Wildenauer, P., Wand, S., Heyne, T., Walliser, K., ... & Roessler, M. (2016). The pre-hospital administration of tranexamic acid to patients with multiple injuries and its effects on rotational thrombelastometry: a prospective observational study in pre-hospital emergency medicine. Scandinavian journal of trauma, resuscitation and emergency medicine, 24(1), 122.
18. Lamba, S., Nagurka, R., Offin, M., & Scott, S. R. (2015). Structured communication: teaching delivery of difficult news with simulated resuscitations in an Emergency Medicine Clerkship. Western Journal of Emergency Medicine, 16(2), 344.
19. Lammers, D., Henry, R., McClellan, J., Armen, S., Koch, E., Sulava, E., ... & Holcomb, J. B. (2023). Prolonged tourniquet use in extremity trauma: What you need to know. Journal of Trauma and Acute Care Surgery, 10-1097.
20. Lee, K. R., & Kim, E. J. (2020). Relationship between interprofessional communication and team task performance. Clinical Simulation in Nursing, 43, 44-50.
21. Magnusson, C., Herlitz, J., Axelsson, C., Höglind, R., Lökholm, E., Hörnfeldt, T. H., ... & Wennberg, P. (2024). Added predictive value of prehospital measurement of point-of-care lactate in an adult general EMS population in Sweden: a multi-centre observational study. Scandinavian journal of trauma, resuscitation and emergency medicine, 32(1), 72.
22. Massey, D., Aitken, L. M., & Chaboyer, W. (2015). The impact of a nurse led rapid response system on adverse, major adverse events and activation of the medical emergency team. Intensive and Critical Care Nursing, 31(2), 83-90.
23. Mazzone, E. (2024). Integrating Psma Expression Patterns, Morphological And Clinical Features To Optimize Detection Of Nodal Metastases In Patients Treated With Psma Radio-Guided Robot-Assisted Radical Prostatectomy And Extended Pelvic Lymph Node Dissection.
24. Morgan, O., Yarham, E., Hudson, A., & Cole, E. (2021). Do pre-hospital physicians improve mortality in major trauma patients? A systematic review. Trauma, 23(1), 3-12.
25. O’Brien, B., Bevan, K., Brockington, C., Murphy, J., & Gilbert, R. (2023). Effects of simulation-based cardiopulmonary and respiratory case training experiences on interprofessional teamwork: a systematic review. Canadian Journal of Respiratory Therapy: CJRT= Revue Canadienne de la Thérapie Respiratoire: RCTR, 59, 85.
26. Ortmann, M. J., Johnson, E. G., Jarrell, D. H., Bilhimer, M., Hayes, B. D., Mishler, A., ... & Zimmerman, D. E. (2021). ASHP guidelines on emergency medicine pharmacist services. American Journal of Health-System Pharmacy, 78(3), 261-275.
27. Otudi, M. I. A., Alanezi, A. A. F., Alogdi, M. A. A., Alotaibi, N. M. H., Almutairi, M. R., Aloneze, K. A., ... & Alfahadi, F. J. (2024). Optimizing Interprofessional Trauma Care Pathways: A Systematic Review of Workflow Integration from Prehospital Stabilization to Definitive Disposition. Saudi Journal of Medicine and Public Health, 1(2), 1359-1364.
28. Öztürk, A., & Demirci, G. (2023). Determining the turnaround time in a newly established biochemistry laboratory. Archives of Current Medical Research, 4(3), 153-177.
29. Raymond, J., Parrein, P., Barat, E., Chenailler, C., Decreau-Gaillon, G., Varin, R., & Joly, L. M. (2023, November). Pharmacist tracking and correction of medication errors: an improvement project in the observation ward of the emergency department. In Annales Pharmaceutiques Françaises (Vol. 81, No. 6, pp. 1007-1017). Elsevier Masson.
30. Rech, M. A., Adams, W., Smetana, K. S., Gurnani, P. K., Patel, M. A. V. B., Peppard, W. J., ... & Flannery, A. H. (2021). Pharmacist avoidance or reductions in medical costs in patients presenting the emergency department: PHARM-EM study. Critical Care Explorations, 3(4), e0406.
31. Rogers, L. M. (2020). Exploring the Role of Medical Scribes on ED Patient Flow and Provider Productivity (Doctoral dissertation, Brandman University).
32. Rosen, M. A., DiazGranados, D., Dietz, A. S., Benishek, L. E., Thompson, D., Pronovost, P. J., & Weaver, S. J. (2018). Teamwork in healthcare: Key discoveries enabling safer, high-quality care. American Psychologist, 73(4), 433.
33. Samadbeik, M., Staib, A., Boyle, J., Khanna, S., Bosley, E., Bodnar, D., ... & Sullivan, C. (2024). Patient flow in emergency departments: a comprehensive umbrella review of solutions and challenges across the health system. BMC health services research, 24(1), 274.
34. Schilling, S., Armaou, M., Morrison, Z., Carding, P., Bricknell, M., & Connelly, V. (2022). Understanding teamwork in rapidly deployed interprofessional teams in intensive and acute care: A systematic review of reviews. Plos one, 17(8), e0272942.
35. Schouten, A. M., Flipse, S. M., van Nieuwenhuizen, K. E., Jansen, F. W., van der Eijk, A. C., & van den Dobbelsteen, J. J. (2023). Operating room performance optimization metrics: a systematic review. Journal of Medical Systems, 47(1), 19.
36. Seymour, C. W., Liu, V. X., Iwashyna, T. J., Brunkhorst, F. M., Rea, T. D., Scherag, A., ... & Angus, D. C. (2016). Assessment of clinical criteria for sepsis: for the third international consensus definitions for sepsis and septic shock (Sepsis-3). Jama, 315(8), 762-774.
37. Shiell, A., Fry, M., Elliott, D., & Elliott, R. (2022). Exploration of a rapid response team model of care: A descriptive dual methods study. Intensive and Critical Care Nursing, 73, 103294.
38. Sirikul, W., Piankusol, C., Wittayachamnankul, B., Riyapan, S., Supasaovapak, J., Wongtanasarasin, W., & McNally, B. (2022). A retrospective multi-centre cohort study: Pre-hospital survival factors of out-of-hospital cardiac arrest (OHCA) patients in Thailand. Resuscitation plus, 9, 100196.
39. Sprogis, S. K., Currey, J., Jones, D., & Considine, J. (2021). Use of the pre-medical emergency team tier of rapid response systems: a scoping review. Intensive and Critical Care Nursing, 65, 103041.
40. Strandmark, R., Herlitz, J., Axelsson, C., Claesson, A., Bremer, A., Karlsson, T., ... & Ravn-Fischer, A. (2015). Determinants of pre-hospital pharmacological intervention and its association with outcome in acute myocardial infarction. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 23(1), 105.
41. Thomas, A., Heraud, F., Gros, S., Allenet, B., & Lesage, P. (2022). Les urgences, carrefour stratégique pour la conciliation médicamenteuse et la pharmacie clinique. Le Pharmacien Clinicien, 57(4), e55.
42. Vitale, E., & Cannito, G. (2020). Observational study of the handover with the SBAR method at Bari Polyclinic complex. Professioni Infermieristiche, 73(1), 27-32.
43. Waydhas, C., Hermes, C., Kumpf, O., Mutlak, H., Spannagl, M., Walcher, F., & Luppa, P. B. (2024). Position paper of DGKL and DIVI on requirements for laboratory services in intensive care and emergency medicine. Medizinische Klinik, Intensivmedizin und Notfallmedizin, 120(1), 47.
44. Weatherburn, D. C. (2023). The role of the intensive care nurse in the medical emergency team: A constructivist grounded theory study. Australian Critical Care, 36(1), 119-126.
45. Won, Y. H., & Kang, J. (2022). Development of a comprehensive model for the role of the rapid response team nurse. Intensive and Critical Care Nursing, 68, 103136.
46. Wu, Y., Wang, J., Luo, F., Li, D., Ran, X., Ren, X., ... & Wei, J. (2022). Construct and clinical verification of a nurse-led rapid response systems and activation criteria. BMC nursing, 21(1), 311.
47. YEMDD. (2024). Is an "Emergency Medicine Pharmacist" essential? Journal of Emergency Medicine and Critical Care, 12(2), 45–52.