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Copyright (c) 2024 Yasser Mohammed Al Dosari, Aloush Assaf Rashid Al-Otaibi, Nasser Saif Alotaibi, Mujahid Ahmed Alhazmi, Safer Atif Alqahtani, Sultan Abdulrahman Obied Alnazawa, Fouad Zaid Aloufi, Hani Ahmed Abdulrahman Almasabi, Abdullah Abid Alotaibi, Huda Ahmad Haj Atti, Mariam Siddig Mohammad Kholi, Tahani Saleh Belal Alzhrani

This work is licensed under a Creative Commons Attribution 4.0 International License.
A Narrative Review: Mapping an Integrated, Multidisciplinary Pathway for the Early Detection and Management of Incidentalomas in Primary Care
Corresponding Author(s) : Yasser Mohammed Al Dosari
Saudi Journal of Medicine and Public Health,
Vol. 1 No. 2 (2024)
Abstract
Background: The proliferation of advanced diagnostic imaging has led to a significant increase in incidental findings, or incidentalomas. These unexpected discoveries, often in asymptomatic patients, present a complex clinical dilemma, creating potential patient anxiety, driving further potentially unnecessary investigations, and straining healthcare resources. Current management is frequently fragmented, lacking standardized protocols that actively integrate the core primary care team members. Aim: This narrative review aims to synthesize existing evidence to propose a standardized, patient-centric, multidisciplinary workflow for managing incidentalomas from detection to resolution, explicitly defining the roles of the General Practitioner (GP), Radiologist, Nurse, Pharmacist, and Health Assistant. Methods: A comprehensive literature search was conducted across PubMed, Scopus, and CINAHL databases for English-language articles published between 2010 and 2024. Keywords included "incidentaloma," "incidental finding," "multidisciplinary," "primary care," "patient navigation," and profession-specific terms. Results: The review identifies critical gaps in communication, patient support, and care coordination. It maps a novel five-pillar pathway: 1) Standardized Radiological Reporting & Risk Stratification, 2) GP-mediated Patient Counseling & Shared Decision-Making, 3) Nurse-led Coordination & Psychological Support, 4) Pharmacist-led Medication Safety Review, and 5) Health Assistant-driven Logistics Management. Two conceptual tables summarize role-specific interventions and a proposed staging protocol. Conclusion: An integrated pathway that leverages the complementary skills of all five primary care professions can significantly reduce patient anxiety, minimize unnecessary interventions, improve adherence to follow-up, and optimize resource utilization. Implementing such a model requires systemic changes in communication infrastructure, interprofessional education, and clinical governance.
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- 1. Al Hussein Al Awamlh, B., Wu, X., Barocas, D. A., Moses, K. A., Hoffman, R. M., Basourakos, S. P., ... & Shoag, J. E. (2023). Intensity of observation with active surveillance or watchful waiting in men with prostate cancer in the United States. Prostate cancer and prostatic diseases, 26(2), 395-402. https://doi.org/10.1038/s41391-022-00580-z
- 2. Berland, L. L., et al. (2018). Managing incidental findings on abdominal CT: White paper of the ACR incidental findings committee. Journal of the American College of Radiology, 15(2), 384-390.
- 3. Bomhof, C. H., Van Bodegom, L., Vernooij, M. W., Pinxten, W. I. M., De Beaufort, I. D., & Bunnik, E. M. (2020). The impact of incidental findings detected during brain imaging on research participants of the Rotterdam study: an interview study. Cambridge Quarterly of Healthcare Ethics, 29(4), 542-556. doi:10.1017/S0963180120000304
- 4. Cambos, S., & Tabarin, A. (2020). Management of adrenal incidentalomas: Working through uncertainty. Best Practice & Research Clinical Endocrinology & Metabolism, 34(3), 101427. https://doi.org/10.1016/j.beem.2020.101427
- 5. Clark, S. D., Reuland, D. S., Brenner, A. T., & Jonas, D. E. (2022). Effect of incidental findings information on lung cancer screening intent: a randomized controlled trial. Journal of General Internal Medicine, 37(14), 3676-3683. https://doi.org/10.1007/s11606-022-07409-4
- 6. Crable, E. L., Feeney, T., Harvey, J., Grim, V., Drainoni, M. L., Walkey, A. J., ... & Drake, F. T. (2021). Management strategies to promote follow-up care for incidental findings: a scoping review. Journal of the American College of Radiology, 18(4), 566-579. https://doi.org/10.1016/j.jacr.2020.11.006
- 7. Davidson, J. C., Rahim, S., Hanks, S. E., Patel, I. J., Tam, A. L., Walker, T. G., ... & Sarode, R. (2019). Society of interventional radiology consensus guidelines for the periprocedural management of thrombotic and bleeding risk in patients undergoing percutaneous image-guided interventions—Part I: Review of anticoagulation agents and clinical considerations: Endorsed by the Canadian Association for Interventional Radiology and the Cardiovascular and Interventional Radiological Society of Europe. Journal of Vascular and Interventional Radiology, 30(8), 1155-1167. https://doi.org/10.1016/j.jvir.2019.04.016
- 8. Durante, C., Grani, G., Lamartina, L., Filetti, S., Mandel, S. J., & Cooper, D. S. (2018). The diagnosis and management of thyroid nodules: a review. Jama, 319(9), 914-924. doi:10.1001/jama.2018.0898
- 9. Epstein, R. M., & Gramling, R. E. (2013). What is shared in shared decision making? Complex decisions when the evidence is unclear. Medical care research and review, 70(1_suppl), 94S-112S. https://doi.org/10.1177/1077558712459216
- 10. Evans, C. S., Arthur, R., Kane, M., Omofoye, F., Chung, A. E., Moreton, E., & Moore, C. (2022). Incidental radiology findings on computed tomography studies in emergency department patients: a systematic review and meta-analysis. Annals of Emergency Medicine, 80(3), 243-256. https://doi.org/10.1016/j.annemergmed.2022.03.027
- 11. Fassnacht, M., Arlt, W., Bancos, I., Dralle, H., Newell-Price, J., Sahdev, A., ... & Dekkers, O. M. (2016). Management of adrenal incidentalomas: European society of endocrinology clinical practice guideline in collaboration with the European network for the study of adrenal tumors. European journal of endocrinology, 175(2), G1-G34. https://doi.org/10.1530/EJE-16-0467
- 12. Feeney, T., Madiedo, A., Knapp, P. E., Gupta, A., McAneny, D., & Drake, F. T. (2022). Incidental adrenal masses: adherence to guidelines and methods to improve initial follow-up: a systematic review. Journal of Surgical Research, 269, 18-27. https://doi.org/10.1016/j.jss.2021.07.041
- 13. Fei, X., Chen, P., Wei, L., Huang, Y., Xin, Y., & Li, J. (2022). Quality management of pulmonary nodule radiology reports based on natural language processing. Bioengineering, 9(6), 244. https://doi.org/10.3390/bioengineering9060244
- 14. Gibney, B. T., Roberts, J. M., D'Ortenzio, R. M., Sheikh, A. M., Nicolaou, S., Roberge, E. A., & O'Neill, S. B. (2021). Preventing and mitigating radiology system failures: a guide to disaster planning. RadioGraphics, 41(7), 2111-2126. https://doi.org/10.1148/rg.2021210083
- 15. Gibson, L. M., Paul, L., Chappell, F. M., Macleod, M., Whiteley, W. N., Salman, R. A. S., ... & Sudlow, C. L. (2018). Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis. Bmj, 363. https://doi.org/10.1136/bmj.k4577
- 16. Gunn, A. J., Mangano, M. D., Choy, G., & Sahani, D. V. (2015). Rethinking the role of the radiologist: enhancing visibility through both traditional and nontraditional reporting practices. Radiographics, 35(2), 416-423. https://doi.org/10.1148/rg.352140042
- 17. Kampalath, R., Roth, B., Nakashima, K., Lee, S., Houshyar, R., & Shieh, S. (2022). The incidental findings coordinator: how a radiology nurse can add value and promote patient safety. Journal of Radiology Nursing, 41(1), 28-32. https://doi.org/10.1016/j.jradnu.2021.12.007
- 18. Kang, S. K., Berland, L. L., Mayo-Smith, W. W., Hoang, J. K., Herts, B. R., Megibow, A. J., & Pandharipande, P. V. (2019). Navigating uncertainty in the management of incidental findings. Journal of the American College of Radiology, 16(5), 700-708. https://doi.org/10.1016/j.jacr.2018.09.042
- 19. Loeb, S., Curnyn, C., Fagerlin, A., Braithwaite, R. S., Schwartz, M. D., Lepor, H., ... & Sedlander, E. (2018). Informational needs during active surveillance for prostate cancer: a qualitative study. Patient education and counseling, 101(2), 241-247. https://doi.org/10.1016/j.pec.2017.08.022
- 20. Lowenstein, L. M., Choi, N. J., Hoffman, K. E., Volk, R. J., & Loeb, S. (2021). Factors that influence clinicians’ decisions to decrease active surveillance monitoring frequency or transition to watchful waiting for localised prostate cancer: a qualitative study. BMJ open, 11(11), e048347. https://doi.org/10.1136/bmjopen-2020-048347
- 21. Lumbreras, B., Donat, L., & Hernández-Aguado, I. (2010). Incidental findings in imaging diagnostic tests: a systematic review. The British journal of radiology, 83(988), 276-289. https://doi.org/10.1259/bjr/98067945
- 22. MacMahon, H., Naidich, D. P., Goo, J. M., Lee, K. S., Leung, A. N., Mayo, J. R., ... & Bankier, A. A. (2017). Guidelines for management of incidental pulmonary nodules detected on CT images: from the Fleischner Society 2017. Radiology, 284(1), 228-243. https://doi.org/10.1148/radiol.2017161659
- 23. Mehta, H. J., Mohammed, T. L., & Jantz, M. A. (2017). The American College of Radiology lung imaging reporting and data system: potential drawbacks and need for revision. Chest, 151(3), 539-543. https://doi.org/10.1016/j.chest.2016.07.028
- 24. Moore, C. L., Baskin, A., Chang, A. M., Cheung, D., Davis, M. A., Fertel, B. S., ... & Nicola, L. P. (2023). White paper: best practices in the communication and management of actionable incidental findings in emergency department imaging. Journal of the American College of Radiology, 20(4), 422-430. https://doi.org/10.1016/j.jacr.2023.01.001
- 25. Ortel, T. L., Neumann, I., Ageno, W., Beyth, R., Clark, N. P., Cuker, A., ... & Zhang, Y. (2020). American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism. Blood advances, 4(19), 4693-4738. https://doi.org/10.1182/bloodadvances.2020001830
- 26. O’Sullivan, J. W., Albasri, A., Nicholson, B. D., Perera, R., Aronson, J. K., Roberts, N., & Heneghan, C. (2018). Overtesting and undertesting in primary care: a systematic review and meta-analysis. BMJ open, 8(2), e018557. https://doi.org/10.1136/bmjopen-2017-018557
- 27. Park, S. S., & Kim, J. H. (2023). Recent updates on the management of adrenal incidentalomas. Endocrinology and Metabolism, 38(4), 373-380. https://doi.org/10.3803/EnM.2023.1779
- 28. Passey, D. G., Healy, R., Qualls, J., Halwani, A., & Sauer, B. C. (2021). Pharmacist-led collaborative medication management programs for oral antineoplastic therapies: a systematic literature review. Journal of the American Pharmacists Association, 61(3), e7-e18. https://doi.org/10.1016/j.japh.2020.12.005
- 29. Prades, J., Morando, V., Tozzi, V. D., Verhoeven, D., Germà, J. R., & Borras, J. M. (2018). Managing cancer care through service delivery networks: the role of professional collaboration in two European cancer networks. Health services management research, 31(3), 120-129. https://doi.org/10.1177/0951484817745219
- 30. Ramirez, M., Wu, S., Ryan, G., Towfighi, A., & Vickrey, B. G. (2017). Using beta-version mHealth technology for team-based care management to support stroke prevention: an assessment of utility and challenges. JMIR research protocols, 6(5), e7106. https://doi.org/10.2196/resprot.7106
- 31. Segelov, E., Guren, M. G., Sebag-Montefiore, D., Rao, S., Johnsson, A., Franco, P., ... & Spindler, K. L. G. (2022). “Global Multidisciplinary Team Meetings”: Challenging Cases Virtual Forums from the International Multidisciplinary Anal Cancer Conference (IMACC). Clinical Colorectal Cancer, 21(3), 175-187. https://doi.org/10.1016/j.clcc.2022.02.006
- 32. Siegmund, L. A., Hamilton, A., & Nespeca, T. (2020). Incidental Findings Coordinator: A New Role for Advanced Practice Registered Nurses. Online Journal of Issues in Nursing, 25(2). DOI: 10.3912/OJIN.Vol25No02PPT5422
- 33. Silverman, S. G., Pedrosa, I., Ellis, J. H., Hindman, N. M., Schieda, N., Smith, A. D., ... & Davenport, M. S. (2019). Bosniak classification of cystic renal masses, version 2019: an update proposal and needs assessment. Radiology, 292(2), 475-488. https://doi.org/10.1148/radiol.2019182646
- 34. Sirimsi, M. M., De Loof, H., Van den Broeck, K., De Vliegher, K., Pype, P., Remmen, R., & Van Bogaert, P. (2022). Scoping review to identify strategies and interventions improving interprofessional collaboration and integration in primary care. BMJ open, 12(10), e062111. https://doi.org/10.1136/bmjopen-2022-062111
- 35. Talutis, S. D., Childs, E., Goldman, A. L., Knapp, P. E., Gupta, A., Ferrao, C., ... & Drake, F. T. (2022). Strategies to optimize management of incidental radiographic findings in the primary care setting: a mixed methods study. The American Journal of Surgery, 223(2), 297-302. https://doi.org/10.1016/j.amjsurg.2021.03.038
- 36. Voltan, G., Boscaro, M., Armanini, D., Scaroni, C., & Ceccato, F. (2021). A multidisciplinary approach to the management of adrenal incidentaloma. Expert Review of Endocrinology & Metabolism, 16(4), 201-212. https://doi.org/10.1080/17446651.2021.1948327
- 37. Wagner, E. H. (2000). The role of patient care teams in chronic disease management. Bmj, 320(7234), 569-572. https://doi.org/10.1136/bmj.320.7234.569
- 38. Wiener, R. S., Gould, M. K., Woloshin, S., Schwartz, L. M., & Clark, J. A. (2015). ‘The thing is not knowing’: patients' perspectives on surveillance of an indeterminate pulmonary nodule. Health Expectations, 18(3), 355-365. https://doi.org/10.1111/hex.12036
References
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2. Berland, L. L., et al. (2018). Managing incidental findings on abdominal CT: White paper of the ACR incidental findings committee. Journal of the American College of Radiology, 15(2), 384-390.
3. Bomhof, C. H., Van Bodegom, L., Vernooij, M. W., Pinxten, W. I. M., De Beaufort, I. D., & Bunnik, E. M. (2020). The impact of incidental findings detected during brain imaging on research participants of the Rotterdam study: an interview study. Cambridge Quarterly of Healthcare Ethics, 29(4), 542-556. doi:10.1017/S0963180120000304
4. Cambos, S., & Tabarin, A. (2020). Management of adrenal incidentalomas: Working through uncertainty. Best Practice & Research Clinical Endocrinology & Metabolism, 34(3), 101427. https://doi.org/10.1016/j.beem.2020.101427
5. Clark, S. D., Reuland, D. S., Brenner, A. T., & Jonas, D. E. (2022). Effect of incidental findings information on lung cancer screening intent: a randomized controlled trial. Journal of General Internal Medicine, 37(14), 3676-3683. https://doi.org/10.1007/s11606-022-07409-4
6. Crable, E. L., Feeney, T., Harvey, J., Grim, V., Drainoni, M. L., Walkey, A. J., ... & Drake, F. T. (2021). Management strategies to promote follow-up care for incidental findings: a scoping review. Journal of the American College of Radiology, 18(4), 566-579. https://doi.org/10.1016/j.jacr.2020.11.006
7. Davidson, J. C., Rahim, S., Hanks, S. E., Patel, I. J., Tam, A. L., Walker, T. G., ... & Sarode, R. (2019). Society of interventional radiology consensus guidelines for the periprocedural management of thrombotic and bleeding risk in patients undergoing percutaneous image-guided interventions—Part I: Review of anticoagulation agents and clinical considerations: Endorsed by the Canadian Association for Interventional Radiology and the Cardiovascular and Interventional Radiological Society of Europe. Journal of Vascular and Interventional Radiology, 30(8), 1155-1167. https://doi.org/10.1016/j.jvir.2019.04.016
8. Durante, C., Grani, G., Lamartina, L., Filetti, S., Mandel, S. J., & Cooper, D. S. (2018). The diagnosis and management of thyroid nodules: a review. Jama, 319(9), 914-924. doi:10.1001/jama.2018.0898
9. Epstein, R. M., & Gramling, R. E. (2013). What is shared in shared decision making? Complex decisions when the evidence is unclear. Medical care research and review, 70(1_suppl), 94S-112S. https://doi.org/10.1177/1077558712459216
10. Evans, C. S., Arthur, R., Kane, M., Omofoye, F., Chung, A. E., Moreton, E., & Moore, C. (2022). Incidental radiology findings on computed tomography studies in emergency department patients: a systematic review and meta-analysis. Annals of Emergency Medicine, 80(3), 243-256. https://doi.org/10.1016/j.annemergmed.2022.03.027
11. Fassnacht, M., Arlt, W., Bancos, I., Dralle, H., Newell-Price, J., Sahdev, A., ... & Dekkers, O. M. (2016). Management of adrenal incidentalomas: European society of endocrinology clinical practice guideline in collaboration with the European network for the study of adrenal tumors. European journal of endocrinology, 175(2), G1-G34. https://doi.org/10.1530/EJE-16-0467
12. Feeney, T., Madiedo, A., Knapp, P. E., Gupta, A., McAneny, D., & Drake, F. T. (2022). Incidental adrenal masses: adherence to guidelines and methods to improve initial follow-up: a systematic review. Journal of Surgical Research, 269, 18-27. https://doi.org/10.1016/j.jss.2021.07.041
13. Fei, X., Chen, P., Wei, L., Huang, Y., Xin, Y., & Li, J. (2022). Quality management of pulmonary nodule radiology reports based on natural language processing. Bioengineering, 9(6), 244. https://doi.org/10.3390/bioengineering9060244
14. Gibney, B. T., Roberts, J. M., D'Ortenzio, R. M., Sheikh, A. M., Nicolaou, S., Roberge, E. A., & O'Neill, S. B. (2021). Preventing and mitigating radiology system failures: a guide to disaster planning. RadioGraphics, 41(7), 2111-2126. https://doi.org/10.1148/rg.2021210083
15. Gibson, L. M., Paul, L., Chappell, F. M., Macleod, M., Whiteley, W. N., Salman, R. A. S., ... & Sudlow, C. L. (2018). Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis. Bmj, 363. https://doi.org/10.1136/bmj.k4577
16. Gunn, A. J., Mangano, M. D., Choy, G., & Sahani, D. V. (2015). Rethinking the role of the radiologist: enhancing visibility through both traditional and nontraditional reporting practices. Radiographics, 35(2), 416-423. https://doi.org/10.1148/rg.352140042
17. Kampalath, R., Roth, B., Nakashima, K., Lee, S., Houshyar, R., & Shieh, S. (2022). The incidental findings coordinator: how a radiology nurse can add value and promote patient safety. Journal of Radiology Nursing, 41(1), 28-32. https://doi.org/10.1016/j.jradnu.2021.12.007
18. Kang, S. K., Berland, L. L., Mayo-Smith, W. W., Hoang, J. K., Herts, B. R., Megibow, A. J., & Pandharipande, P. V. (2019). Navigating uncertainty in the management of incidental findings. Journal of the American College of Radiology, 16(5), 700-708. https://doi.org/10.1016/j.jacr.2018.09.042
19. Loeb, S., Curnyn, C., Fagerlin, A., Braithwaite, R. S., Schwartz, M. D., Lepor, H., ... & Sedlander, E. (2018). Informational needs during active surveillance for prostate cancer: a qualitative study. Patient education and counseling, 101(2), 241-247. https://doi.org/10.1016/j.pec.2017.08.022
20. Lowenstein, L. M., Choi, N. J., Hoffman, K. E., Volk, R. J., & Loeb, S. (2021). Factors that influence clinicians’ decisions to decrease active surveillance monitoring frequency or transition to watchful waiting for localised prostate cancer: a qualitative study. BMJ open, 11(11), e048347. https://doi.org/10.1136/bmjopen-2020-048347
21. Lumbreras, B., Donat, L., & Hernández-Aguado, I. (2010). Incidental findings in imaging diagnostic tests: a systematic review. The British journal of radiology, 83(988), 276-289. https://doi.org/10.1259/bjr/98067945
22. MacMahon, H., Naidich, D. P., Goo, J. M., Lee, K. S., Leung, A. N., Mayo, J. R., ... & Bankier, A. A. (2017). Guidelines for management of incidental pulmonary nodules detected on CT images: from the Fleischner Society 2017. Radiology, 284(1), 228-243. https://doi.org/10.1148/radiol.2017161659
23. Mehta, H. J., Mohammed, T. L., & Jantz, M. A. (2017). The American College of Radiology lung imaging reporting and data system: potential drawbacks and need for revision. Chest, 151(3), 539-543. https://doi.org/10.1016/j.chest.2016.07.028
24. Moore, C. L., Baskin, A., Chang, A. M., Cheung, D., Davis, M. A., Fertel, B. S., ... & Nicola, L. P. (2023). White paper: best practices in the communication and management of actionable incidental findings in emergency department imaging. Journal of the American College of Radiology, 20(4), 422-430. https://doi.org/10.1016/j.jacr.2023.01.001
25. Ortel, T. L., Neumann, I., Ageno, W., Beyth, R., Clark, N. P., Cuker, A., ... & Zhang, Y. (2020). American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism. Blood advances, 4(19), 4693-4738. https://doi.org/10.1182/bloodadvances.2020001830
26. O’Sullivan, J. W., Albasri, A., Nicholson, B. D., Perera, R., Aronson, J. K., Roberts, N., & Heneghan, C. (2018). Overtesting and undertesting in primary care: a systematic review and meta-analysis. BMJ open, 8(2), e018557. https://doi.org/10.1136/bmjopen-2017-018557
27. Park, S. S., & Kim, J. H. (2023). Recent updates on the management of adrenal incidentalomas. Endocrinology and Metabolism, 38(4), 373-380. https://doi.org/10.3803/EnM.2023.1779
28. Passey, D. G., Healy, R., Qualls, J., Halwani, A., & Sauer, B. C. (2021). Pharmacist-led collaborative medication management programs for oral antineoplastic therapies: a systematic literature review. Journal of the American Pharmacists Association, 61(3), e7-e18. https://doi.org/10.1016/j.japh.2020.12.005
29. Prades, J., Morando, V., Tozzi, V. D., Verhoeven, D., Germà, J. R., & Borras, J. M. (2018). Managing cancer care through service delivery networks: the role of professional collaboration in two European cancer networks. Health services management research, 31(3), 120-129. https://doi.org/10.1177/0951484817745219
30. Ramirez, M., Wu, S., Ryan, G., Towfighi, A., & Vickrey, B. G. (2017). Using beta-version mHealth technology for team-based care management to support stroke prevention: an assessment of utility and challenges. JMIR research protocols, 6(5), e7106. https://doi.org/10.2196/resprot.7106
31. Segelov, E., Guren, M. G., Sebag-Montefiore, D., Rao, S., Johnsson, A., Franco, P., ... & Spindler, K. L. G. (2022). “Global Multidisciplinary Team Meetings”: Challenging Cases Virtual Forums from the International Multidisciplinary Anal Cancer Conference (IMACC). Clinical Colorectal Cancer, 21(3), 175-187. https://doi.org/10.1016/j.clcc.2022.02.006
32. Siegmund, L. A., Hamilton, A., & Nespeca, T. (2020). Incidental Findings Coordinator: A New Role for Advanced Practice Registered Nurses. Online Journal of Issues in Nursing, 25(2). DOI: 10.3912/OJIN.Vol25No02PPT5422
33. Silverman, S. G., Pedrosa, I., Ellis, J. H., Hindman, N. M., Schieda, N., Smith, A. D., ... & Davenport, M. S. (2019). Bosniak classification of cystic renal masses, version 2019: an update proposal and needs assessment. Radiology, 292(2), 475-488. https://doi.org/10.1148/radiol.2019182646
34. Sirimsi, M. M., De Loof, H., Van den Broeck, K., De Vliegher, K., Pype, P., Remmen, R., & Van Bogaert, P. (2022). Scoping review to identify strategies and interventions improving interprofessional collaboration and integration in primary care. BMJ open, 12(10), e062111. https://doi.org/10.1136/bmjopen-2022-062111
35. Talutis, S. D., Childs, E., Goldman, A. L., Knapp, P. E., Gupta, A., Ferrao, C., ... & Drake, F. T. (2022). Strategies to optimize management of incidental radiographic findings in the primary care setting: a mixed methods study. The American Journal of Surgery, 223(2), 297-302. https://doi.org/10.1016/j.amjsurg.2021.03.038
36. Voltan, G., Boscaro, M., Armanini, D., Scaroni, C., & Ceccato, F. (2021). A multidisciplinary approach to the management of adrenal incidentaloma. Expert Review of Endocrinology & Metabolism, 16(4), 201-212. https://doi.org/10.1080/17446651.2021.1948327
37. Wagner, E. H. (2000). The role of patient care teams in chronic disease management. Bmj, 320(7234), 569-572. https://doi.org/10.1136/bmj.320.7234.569
38. Wiener, R. S., Gould, M. K., Woloshin, S., Schwartz, L. M., & Clark, J. A. (2015). ‘The thing is not knowing’: patients' perspectives on surveillance of an indeterminate pulmonary nodule. Health Expectations, 18(3), 355-365. https://doi.org/10.1111/hex.12036