Ghon Complex: Clinical Significance and Nursing Management-An Updated Review
Abstract
Background: The Ghon complex represents the classic pathological and radiological hallmark of primary pulmonary tuberculosis (TB), reflecting the interaction between Mycobacterium tuberculosis and host immunity. Recognition of this entity remains clinically relevant, particularly for early diagnosis, infection control, and prevention of disease progression or transmission.
Aim: This review aims to examine the clinical significance of the Ghon complex and highlight nursing, allied health, and interprofessional roles in its detection, management, and monitoring.
Methods: An updated narrative review of radiological, histopathological, and clinical evidence regarding the Ghon complex was conducted, with emphasis on diagnostic approaches, nursing interventions, infection prevention measures, and interprofessional collaboration in tuberculosis care.
Results: The Ghon complex commonly presents as a subpleural parenchymal lesion with regional lymphadenopathy and may progress to latency, healing, or active disease. Radiographic findings are variable and may be absent in some cases, complicating diagnosis. Nurses play a pivotal role in early recognition, symptom screening, isolation initiation, patient education, treatment adherence, and longterm monitoring, thereby reducing nosocomial transmission and improving outcomes.
Conclusion: Understanding the Ghon complex supports timely diagnosis, effective tuberculosis management, and coordinated interprofessional care.
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Authors
Copyright (c) 2025 Norah Ali Albishi, Kalthom Yahya Bakar Abdullah, Ashwaq Ruwayshid Alanazi, Eman Ali Ahmad, Mai Mahdi Alshammari, Hamsaa Alhumaidi Alqahtani, Alanoud Mohammed, MISHARI ALMUTAIRI, Reem Mohammad Ali Alshehri, THALLAB ALMUTAIRI, Saud Faisal Almutairi, Safia Ibrahim Alfifi
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