The Precision Pipeline: Orchestrating Interprofessional Coordination from Administrative Hub to Genomic Therapeutics in Oncology
Abstract
Background: The contemporary cancer care trajectory has evolved into a high-stakes "precision pipeline," a multi-phase continuum from administrative coordination to the delivery of genomically-guided therapies. This complex pathway necessitates flawless handoffs between diverse professionals, yet systemic fragmentation often undermines safety, timeliness, and therapeutic integrity.
Aim: This narrative review synthesizes current evidence (2010-2024) to critically map and analyze the integrated cancer care coordination pathway, examining the interdependent roles from treatment scheduling and nursing administration through genomic testing to targeted therapy management.
Methods: A comprehensive literature search was conducted across PubMed, CINAHL, and Scopus. Included studies were evaluated and synthesized thematically to identify barriers, facilitators, and outcomes associated with each segment and their coordination.
Results: Optimal pathway performance hinges on interoperable health information systems, standardized communication protocols, and role-specific expertise. Key findings underscore the efficacy of nurse navigation in reducing scheduling delays, the criticality of pre-chemotherapy nursing assessments, the turnaround time of genomic testing as a critical rate-limiting step, and the indispensable role of clinical pharmacists in optimizing targeted therapy outcomes.
Conclusion: A seamless, patient-centered oncology pipeline requires deliberate systemic integration, robust informatics, and profound interprofessional collaboration. Future models must prioritize embedded navigation, real-time data ecosystems, and pharmacist-led therapeutic management to fully realize the promise of precision medicine.
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Copyright (c) 2024 Aziz Hamoud Sari Al-Otaibi, Abdullah Yahya H. Oagde, Nawal Ahmed Yousef Aljarad, Mohammed Yahya Yahya Mahzari, Rana Hassan A Hakami, Manahil Ayed Alshammari, Ghadeer Naif Abdullah Alshammari, Halah Muflih Alrashidi, Anwar Towairsh Eid Aljameeli
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