Integrated Medical and Nursing Perspectives in the Emergency Management of Venous Gas Embolism: A Multidisciplinary Clinical Approach

Mutual Mohamad Khalaf Alrougy (1) , Monif Dhaher Thani Almutrafi (2) , Abdullah Amer B Aldosari (3) , Mona Abolghith Umar Qdaimi (4) , Sarah Mubarak M Aldawsari (5) , Salha Mohammed Al-Thrwy (6) , Fahad Bandar Almutairi (7) , Azzah Atitallah Ali Alzahrani (8) , Sahar Saad Saed Alshahrani (9) , Guzail Masfer Alotibi (10) , Afaf Hassan Alnami (11) , Khalid Nasser Aldhahran (11)
(1) Alrafai General Hospital, Ministry of Health, Saudi Arabia,
(2) ‏King Khaled Hospital In Alkharj, Ministry of Health, Saudi Arabia,
(3) Ministry Of Health, Saudi Arabia,
(4) King Abdullah Complex & Maternity & Children's Hospital, Saudi Arabia,
(5) Primary Health Care Center In Haroub, Ministry of Health, Saudi Arabia,
(6) Harob Phc, Ministry of Health, Saudi Arabia,
(7) Branche Of Ministry Of Health, Riyadh Region., Saudi Arabia,
(8) Al-Malaz Phc , Cluster 1 Al-Riyadh, Ministry of Health, Saudi Arabia,
(9) Primary Health Care Alraied In Rieyadh, Ministry of Health, Saudi Arabia,
(10) Ministry Of Health Al-Quwayiyah General Hospital Umm Sariha Health Center, Saudi Arabia,
(11) Prince Mohammed Bin Nasser  Hospital, Ministry of Health, Saudi Arabia

Abstract

Background: Venous Gas Embolism (VGE) is a critical condition characterized by the entrainment of gas into the venous system, often due to iatrogenic causes like central venous catheterization and neurosurgery. It can lead to right ventricular outflow obstruction, cardiovascular collapse, and, via paradoxical embolism, systemic end-organ ischemia.


Aim: This article aims to synthesize an integrated, multidisciplinary approach to the emergency management of VGE, emphasizing the collaborative roles of medicine and nursing in rapid diagnosis, stabilization, and treatment to improve patient outcomes.


Methods: The review examines the pathophysiology, etiology, and clinical presentation of VGE. It evaluates diagnostic modalities, including continuous capnography and echocardiography, and details a structured management protocol involving immediate source control, patient repositioning, hemodynamic support, and aspiration of intracardiac air.


Results: VGE presents with a spectrum of symptoms, from subtle changes in end-tidal CO₂ to fulminant cardiovascular collapse. Key interventions—administering 100% oxygen, placing the patient in the left lateral decubitus position, and aspirating air via a central venous catheter—are time-critical. Hyperbaric oxygen therapy is a crucial adjunct for severe cases, particularly those with neurological involvement.


Conclusion: Successful management of VGE hinges on a high index of suspicion and immediate, coordinated action by a multidisciplinary team. A protocolized response that integrates medical and nursing expertise is essential to mitigate this life-threatening emergency's high morbidity and mortality.

Full text article

Generated from XML file

References

Ahmed B, Musa A, Ravindrane A, Meer MM. Cerebral Venous Air Embolism: A Rare Clinical Challenge and Management Insights. Cureus. 2024 Nov:16(11):e73621. doi: 10.7759/cureus.73621

Robinson NL, Marcellino C, Johnston M, Abcejo AS. A human cadaveric model for venous air embolism detection tool development. PloS one. 2024:19(10):e0309447. doi: 10.1371/journal.pone.0309447.

Daqour A, Fraij A, Khawaja D, Hussain T, Mabhouh T, Salahaldin M, Saifi M, Abuawad M. Unexpected pulmonary edema following sitting position craniotomy: A venous air embolism complication. Respirology case reports. 2024 Dec:12(12):e70093. doi: 10.1002/rcr2.70093.

Oganov AC, Iyengar NS, Siu NY, Sibony PA. Venous air embolism of the superior ophthalmic vein and cavernous sinus. Orbit (Amsterdam, Netherlands). 2024 Dec 18:():1. doi: 10.1080/01676830.2024.2439327.

Ruiz Avila HA, García-Araque HF, Acosta-Gutiérrez E. Paradoxical venous air embolism detected with point-of-care ultrasound: a case report. The ultrasound journal. 2022 May 18:14(1):19. doi: 10.1186/s13089-022-00265-7.

Bothma PA, Schlimp CJ. Iatrogenic cerebral gas embolism, pneumocephalus and the concept of retrograde cerebral venous gas embolism. Acta anaesthesiologica Scandinavica. 2019 Jul:63(6):831. doi: 10.1111/aas.13331.

Valente-Aguiar MS, Dinis-Oliveira RJ. Massive gas embolism in a child. Forensic science, medicine, and pathology. 2019 Sep:15(3):498-501. doi: 10.1007/s12024-018-0072-x.

Bagdasarov VV, Bagdasarova EA, Protsenko DN, Ketskalo MV, Tavadov AV. [Extracorporeal membrane oxygenation in severe combined trauma complicated by fat embolism]. Khirurgiia. 2018:(10):76-80. doi: 10.17116/hirurgia201810176.

Blake DF, Crowe M, Mitchell SJ, Aitken P, Pollock NW. Vibration and bubbles: a systematic review of the effects of helicopter retrieval on injured divers. Diving and hyperbaric medicine. 2018 Dec 24:48(4):235-240. doi: 10.28920/dhm48.4.241-251.

de Jong KIF, de Leeuw PW. Venous carbon dioxide embolism during laparoscopic cholecystectomy a literature review. European journal of internal medicine. 2019 Feb:60():9-12. doi: 10.1016/j.ejim.2018.10.008.

Jung YC, Kang MW, Cho HJ, Chong Y, Lee JW. Point-of-Care Ultrasonography Detects Vanishing Air Embolism Following Central Venous Catheter Removal in a Patient With Chest Tube Drainage: A Case Report. Clinical case reports. 2025 Jul:13(7):e70578. doi: 10.1002/ccr3.70578.

Červeňák V, Všianský V, Cviková M, Brichta J, Vinklárek J, Štefela J, Haršány M, Hájek M, Herzig R, Kouřil D, Bárková V, Filip P, Aulický P, Weiss V. Cerebral air embolism: neurologic manifestations, prognosis, and outcome. Frontiers in neurology. 2024:15():1417006. doi: 10.3389/fneur.2024.1417006.

Hanks T, Raub S, Hiatt K, Abecassis ZA, Nistal D, Jamshidi AM, Ferreira M Jr, Ruzevick J, Emerson S. Intraoperative venous air embolism during endoscopic transsphenoidal surgery: recommendations for management. Illustrative case. Journal of neurosurgery. Case lessons. 2025 Mar 3:9(9):. pii: CASE24691. doi: 10.3171/CASE24691.

Lim LT, Somerville GM, Walker JD. Venous air embolism during air/fluid exchange: a potentially fatal complication. Archives of ophthalmology (Chicago, Ill. : 1960). 2010 Dec:128(12):1618-9. doi: 10.1001/archophthalmol.2010.273.

Berlot G, Rinaldi A, Moscheni M, Ferluga M, Rossini P. Uncommon Occurrences of Air Embolism: Description of Cases and Review of the Literature. Case reports in critical care. 2018:2018():5808390. doi: 10.1155/2018/5808390.

Gonzalez JJ, Abdelrazzak E, Kesari K. Venous air embolism in a patient with a massive upper gastrointestinal bleeding. BMJ case reports. 2018 Jul 18:2018():. pii: bcr-2018-226570. doi: 10.1136/bcr-2018-226570.

G G, Murthy AS, Yadav A, Babu MN, Dagar S, Gupta SK. Air Embolism in a Case of Pulmonary Aspergillosis-A Case Report With Brief Review of Literature. The American journal of forensic medicine and pathology. 2025 Jun 1:46(2):175-179. doi: 10.1097/PAF.0000000000001036.

Wenham TN, Graham D. Venous gas embolism: An unusual complication of laparoscopic cholecystectomy. Journal of minimal access surgery. 2009 Apr:5(2):35-6. doi: 10.4103/0972-9941.55105.

Moon RE, Mitchell SJ. Hyperbaric Treatment of Air or Gas Embolism: Current Recommendations. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc. 2025 First Quarter:52(1):41-53

Drosos N, Jacob S, Nazir N, George AS. Anesthesiology Considerations and Management of Venous Air Embolism in Patients in the Semisitting Position: A Single-Center Review. Cureus. 2025 Mar:17(3):e81093. doi: 10.7759/cureus.81093.

Fukuda H, Fukushima K, Takahashi Y, Hayakawa A, Tokue H, Obana Y, Iwahara K, Tsuzuki T, Yokoo S, Sano R. Unexpected death from air embolism during routine dental Procedure: A case report. Legal medicine (Tokyo, Japan). 2025 Sep:77():102674. doi: 10.1016/j.legalmed.2025.102674.

Liu SQ, Zhao SZ, Li ZW, Lv SP, Liu YQ, Li Y. Monitoring of Gas Emboli During Hysteroscopic Surgery: A Prospective Study. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 2017 Apr:36(4):749-756. doi: 10.7863/ultra.16.03051.

Hendriksen SM, Menth NL, Westgard BC, Cole JB, Walter JW, Masters TC, Logue CJ. Hyperbaric oxygen therapy for the prevention of arterial gas embolism in food grade hydrogen peroxide ingestion. The American journal of emergency medicine. 2017 May:35(5):809.e5-809.e8. doi: 10.1016/j.ajem.2016.12.027.

Musiał R, Darocha T, Kosiński S, Stoliński J, Sadowski J, Drwiła R. Application of V-A ECMO therapies for short-term mechanical circulatory support in patients with cardiogenic shock. Anaesthesiology intensive therapy. 2015:47(4):324-7. doi: 10.5603/AIT.2015.0046.

Hatipoglu Majernik G, Baskaya MK. A Bibliometric Analysis of Sitting Position and Air Embolism in Neurosurgery: Top 100 Most Cited Articles. World neurosurgery. 2025 May:197():123884. doi: 10.1016/j.wneu.2025.123884.

Ferrara M, Romano V, Longo L, Rovati M, Raimondi R, Semeraro F, Aliberti S, Romano MR. Life-threatening complications in ophthalmic surgery: a systematic review. Eye (London, England). 2025 Jan:39(1):69-78. doi: 10.1038/s41433-024-03442-1. Epub 2024 Nov 23

Ghosh A, Ninave S. Intraoperative Challenge: Managing Venous Air Embolism During Sitting Craniotomy. Cureus. 2024 Jun:16(6):e61484. doi: 10.7759/cureus.61484.

Malik N, Claus PL, Illman JE, Kligerman SJ, Moynagh MR, Levin DL, Woodrum DA, Arani A, Arunachalam SP, Araoz PA. Air embolism: diagnosis and management. Future cardiology. 2017 Jul:13(4):365-378. doi: 10.2217/fca-2017-0015. Epub 2017 Jun 23

Authors

Mutual Mohamad Khalaf Alrougy
Mal-Roqi@Moh.Gov.Sa (Primary Contact)
Monif Dhaher Thani Almutrafi
Abdullah Amer B Aldosari
Mona Abolghith Umar Qdaimi
Sarah Mubarak M Aldawsari
Salha Mohammed Al-Thrwy
Fahad Bandar Almutairi
Azzah Atitallah Ali Alzahrani
Sahar Saad Saed Alshahrani
Guzail Masfer Alotibi
Afaf Hassan Alnami
Khalid Nasser Aldhahran
Alrougy, M. M. K., Monif Dhaher Thani Almutrafi, Abdullah Amer B Aldosari, Mona Abolghith Umar Qdaimi, Sarah Mubarak M Aldawsari, Salha Mohammed Al-Thrwy, … Khalid Nasser Aldhahran. (2025). Integrated Medical and Nursing Perspectives in the Emergency Management of Venous Gas Embolism: A Multidisciplinary Clinical Approach. Saudi Journal of Medicine and Public Health, 2(2), 936–946. https://doi.org/10.64483/202522226

Article Details

Similar Articles

<< < 11 12 13 14 > >> 

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)