‏Post-Pandemic Nosocomial Defense: A Systematic Review of Nursing-Led Multimodal Strategies for Sustainable Infection Prevention

Elham Nasser Ahmad Hadi (1) , Jameelah Ebrahim Mohammad Ayoub , Zahra Yehia Hadi Abumerai , Fawziah Ahmed  Ahmed Jafari , Ohoud Abdullah Mohammed Omeesh , Halimah Mohmmed Bashir , Hanaa Bhees Ali Bhees , Nawal Mohammad Abdullah Basher , Badriah Gassem Hakam , Shagra Jubran Mohammed Abuallh , Nagwa Abduljbar Ali , Ishraq Atia Muhammed Jarab , Fauzea Mohammad Abuhadi , Amna Ahmed Salem , Nawal Ahmed Ayashi
(1) Ministry of Health, Saudi Arabia

Abstract

Background: The COVID-19 pandemic critically exposed and exacerbated vulnerabilities in global healthcare-associated infection (HAI) prevention infrastructures. While infection control is multidisciplinary, nursing, as the constant bedside presence, holds a pivotal and evolving role in the execution and sustainability of fundamental and advanced preventive measures. Aim: This narrative review synthesizes current evidence (2015-2024) on effective, nursing-integrated strategies to reduce HAI rates in the post-pandemic context, focusing on multimodal, systems-oriented approaches. Methods: A comprehensive search of PubMed, CINAHL, and Scopus databases was conducted for English-language literature. Studies evaluating nursing interventions, education models, technological aids, and organizational support structures impacting HAI metrics (e.g., CLABSI, CAUTI, SSI, MRSA) were thematically analyzed. Results: Evidence strongly supports the efficacy of nurse-driven protocols, competency-based education augmented by simulation, and strategic technological integration (e.g., electronic hand hygiene monitoring, clinical decision support). Crucially, success was dependent on foundational elements: sustained nurse staffing and well-being, a just culture of safety, and authentic interdisciplinary collaboration. Post-pandemic, strategies emphasizing antimicrobial stewardship roles for nurses and resilience-building are paramount. Conclusion: Moving beyond crisis-mode response, sustainable infection reduction requires empowering nurses through systemic support, education, and technology. The future lies in embedding robust, nurse-led preventive practices into the fabric of standard care, transforming lessons from the pandemic into durable defense mechanisms against HAIs. 

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References

Ashcraft, S., Bordelon, C., Fells, S., George, V., Thombley, K., & Shirey, M. R. (2017). Interprofessional clinical rounding: effects on processes and outcomes of care. The Journal for Healthcare Quality (JHQ), 39(2), 85-94. DOI: 10.1097/JHQ.0000000000000039

Bartmess, M., Myers, C. R., & Thomas, S. P. (2021, July). Nurse staffing legislation: Empirical evidence and policy analysis. In Nursing forum (Vol. 56, No. 3, pp. 660-675). https://doi.org/10.1111/nuf.12594

Bobbitt, L. J., Cimino, C., Garvey, K. V., Craft, L. S., Eichenseer, N. A., & Nelson, G. E. (2023). An app a day: results of pre-and post-surveys of knowledge, attitudes, and practices (KAP) regarding antimicrobial stewardship principles among nurses who utilized a novel learning platform. Antimicrobial Stewardship & Healthcare Epidemiology, 3(1), e41. doi:10.1017/ash.2023.131

Carter, N., Valaitis, R. K., Lam, A., Feather, J., Nicholl, J., & Cleghorn, L. (2018). Navigation delivery models and roles of navigators in primary care: a scoping literature review. BMC health services research, 18(1), 96. https://doi.org/10.1186/s12913-018-2889-0

Cerles, A. A., Dinh, N. N., MacMillan, L., Kemp, D. C., & Rush, M. A. (2021). Development of novel video-based first responder opioid hazard refresher training. New Solutions: A Journal of Environmental and Occupational Health Policy, 31(3), 298-306. https://doi.org/10.1177/10482911211038336

Despotovic, A., Milosevic, B., Cirkovic, A., Vujovic, A., Cucanic, K., Cucanic, T., & Stevanovic, G. (2021). The impact of COVID-19 on the profile of hospital-acquired infections in adult intensive care units. Antibiotics, 10(10), 1146. https://doi.org/10.3390/antibiotics10101146

Dunn, A. S., Reyna, M., Radbill, B., Parides, M., Colgan, C., Osio, T., ... & Kaplan, H. (2017). The impact of bedside interdisciplinary rounds on length of stay and complications. Journal of hospital medicine, 12(3), 137-142. https://doi.org/10.12788/jhm.2695

Durant, D. J. (2017). Nurse-driven protocols and the prevention of catheter-associated urinary tract infections: a systematic review. American journal of infection control, 45(12), 1331-1341. https://doi.org/10.1016/j.ajic.2017.07.020

Floyd, N. A., Dominguez-Cancino, K. A., Butler, L. G., Rivera-Lozada, O., Leyva-Moral, J. M., & Palmieri, P. A. (2021). The effectiveness of care bundles including the braden scale for preventing hospital acquired pressure ulcers in older adults hospitalized in icus: A Systematic review. The Open Nursing Journal, 15(1). http://dx.doi.org/10.2174/1874434602115010074

Galanis, P., Vraka, I., Fragkou, D., Bilali, A., & Kaitelidou, D. (2021). Nurses' burnout and associated risk factors during the COVID‐19 pandemic: A systematic review and meta‐analysis. Journal of advanced nursing, 77(8), 3286-3302. https://doi.org/10.1111/jan.14839

Greenhalgh, T., Thorne, S., & Malterud, K. (2018). Time to challenge the spurious hierarchy of systematic over narrative reviews?. European journal of clinical investigation, 48(6), e12931. https://doi.org/10.1111/eci.12931

Halverson, T., Mikolajczak, A., Mora, N., Silkaitis, C., & Stout, S. (2022). Impact of COVID-19 on hospital acquired infections. American journal of infection control, 50(7), 831-833. https://doi.org/10.1016/j.ajic.2022.02.030

Han, X., Pittman, P., & Barnow, B. (2021). Alternative approaches to ensuring adequate nurse staffing: The effect of state legislation on hospital nurse staffing. Medical Care, 59, S463-S470. DOI: 10.1097/MLR.0000000000001614

Holbrook, S., O'Brien-Malone, C., Barton, A., & Harper, K. (2021). A quality improvement initiative to reduce hospital-acquired pressure injuries (HAPI) in an acute inpatient setting by improving patient education and seating. Wound Practice & Research: Journal of the Australian Wound Management Association, 29(4), 198-205. https://search.informit.org/doi/10.3316/informit.243061442499537

Ista, E., Van der Hoven, B., Kornelisse, R. F., Van der Starre, C., Vos, M. C., Boersma, E., & Helder, O. K. (2016). Effectiveness of insertion and maintenance bundles to prevent central-line-associated bloodstream infections in critically ill patients of all ages: a systematic review and meta-analysis. The Lancet Infectious Diseases, 16(6), 724-734. https://doi.org/10.1016/S1473-3099(15)00409-0

Jackson, C., Lowton, K., & Griffiths, P. (2014). Infection prevention as “a show”: a qualitative study of nurses’ infection prevention behaviours. International journal of nursing studies, 51(3), 400-408. https://doi.org/10.1016/j.ijnurstu.2013.07.002

Jansson, M. M., Syrjälä, H. P., Ohtonen, P. P., Meriläinen, M. H., Kyngäs, H. A., & Ala-Kokko, T. I. (2016). Simulation education as a single intervention does not improve hand hygiene practices: a randomized controlled follow-up study. American journal of infection control, 44(6), 625-630. https://doi.org/10.1016/j.ajic.2015.12.030

Jones, A. E., Nagle, C., Ahern, T., & Smyth, W. (2023). Evidence for a nurse-led protocol for removing urinary catheters: A scoping review. Collegian, 30(1), 190-197. https://doi.org/10.1016/j.colegn.2022.08.008

Lasater, K. B., Aiken, L. H., Sloane, D., French, R., Martin, B., Alexander, M., & McHugh, M. D. (2021). Patient outcomes and cost savings associated with hospital safe nurse staffing legislation: an observational study. BMJ open, 11(12), e052899. https://doi.org/10.1136/bmjopen-2021-052899

Mittal, N., Deswal, H., Mittal, R., Sharma, S., & Kaushik, P. (2023). An educational program on antimicrobial resistance and stewardship for staff nurses in a public tertiary care hospital in India. Infection, Disease & Health, 28(3), 202-210. https://doi.org/10.1016/j.idh.2023.03.003

Monsees, E., Goldman, J., & Popejoy, L. (2017). Staff nurses as antimicrobial stewards: an integrative literature review. American journal of infection control, 45(8), 917-922. https://doi.org/10.1016/j.ajic.2017.03.009

Murray, J. S., Clifford, J., Larson, S., Lee, J. K., & Sculli, G. L. (2023). Implementing just culture to improve patient safety. Military Medicine, 188(7-8), 1596-1599. https://doi.org/10.1093/milmed/usac115

Ozdemir, N. G., & Kaya, H. (2023). The effectiveness of high-fidelity simulation methods to gain Foley catheterization knowledge, skills, satisfaction and self-confidence among novice nursing students: A randomized controlled trial. Nurse Education Today, 130, 105952. https://doi.org/10.1016/j.nedt.2023.105952

Qureshi, M. O., Chughtai, A. A., & Seale, H. (2022). Recommendations related to occupational infection prevention and control training to protect healthcare workers from infectious diseases: a scoping review of infection prevention and control guidelines. BMC health services research, 22(1), 272. https://doi.org/10.1186/s12913-022-07673-4

Rossley, A. C. (2023). A Comparison of Registered Nurses' Motivation and Knowledge Levels Between Gamified and Traditional Courses (Doctoral dissertation, University of Northern Colorado).

Shen, L., Wang, X., An, J., An, J., Zhou, N., Sun, L., ... & Liu, X. (2017). Implementation of WHO multimodal strategy for improvement of hand hygiene: a quasi-experimental study in a Traditional Chinese Medicine hospital in Xi’an, China. Antimicrobial Resistance & Infection Control, 6(1), 98. https://doi.org/10.1186/s13756-017-0254-4

Shin, S., Park, J. H., & Bae, S. H. (2018). Nurse staffing and nurse outcomes: A systematic review and meta-analysis. Nursing outlook, 66(3), 273-282. https://doi.org/10.1016/j.outlook.2017.12.002

Storr, J., Twyman, A., Zingg, W., Damani, N., Kilpatrick, C., Reilly, J., ... & Allegranzi, B. (2017). Core components for effective infection prevention and control programmes: new WHO evidence-based recommendations. Antimicrobial Resistance & Infection Control, 6(1), 6. https://doi.org/10.1186/s13756-016-0149-9

van Marum, S., Verhoeven, D., & de Rooy, D. (2022). The barriers and enhancers to trust in a just culture in hospital settings: a systematic review. Journal of Patient Safety, 18(7), e1067-e1075. DOI: 10.1097/PTS.0000000000001012

Wang, C., Jiang, W., Yang, K., Yu, D., Newn, J., Sarsenbayeva, Z., ... & Kostakos, V. (2021). Electronic monitoring systems for hand hygiene: systematic review of technology. Journal of Medical Internet Research, 23(11), e27880. https://doi.org/10.2196/27880

Yoshikawa, A., Tashiro, N., Ohtsuka, H., Aoki, K., Togo, S., Komaba, K., ... & Enokida, M. (2022). Protocol for educational programs on infection prevention/control for medical and healthcare student: A systematic review and meta-analysis. PLoS One, 17(10), e0276851. https://doi.org/10.1371/journal.pone.0276851

Zhang, Y., Chen, X., Lao, Y., Qiu, X., Liu, K., Zhuang, Y., ... & Wang, P. (2023). Effects of the implementation of Intelligent Technology for Hand Hygiene in Hospitals: systematic review and Meta-analysis. Journal of Medical Internet Research, 25, e37249. https://doi.org/10.2196/37249

Authors

Elham Nasser Ahmad Hadi
Ehadi@moh.gov.sa (Primary Contact)
Jameelah Ebrahim Mohammad Ayoub
Zahra Yehia Hadi Abumerai
Fawziah Ahmed  Ahmed Jafari
Ohoud Abdullah Mohammed Omeesh
Halimah Mohmmed Bashir
Hanaa Bhees Ali Bhees
Nawal Mohammad Abdullah Basher
Badriah Gassem Hakam
Shagra Jubran Mohammed Abuallh
Nagwa Abduljbar Ali
Ishraq Atia Muhammed Jarab
Fauzea Mohammad Abuhadi
Amna Ahmed Salem
Nawal Ahmed Ayashi
Hadi, E. N. A., Jameelah Ebrahim Mohammad Ayoub, Zahra Yehia Hadi Abumerai, FawziahAhmed AhmedJafari, Ohoud Abdullah Mohammed Omeesh, Halimah Mohmmed Bashir, … Nawal Ahmed Ayashi. (2024). ‏Post-Pandemic Nosocomial Defense: A Systematic Review of Nursing-Led Multimodal Strategies for Sustainable Infection Prevention. Saudi Journal of Medicine and Public Health, 1(2), 1514–1520. https://doi.org/10.64483/202412425

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