Odontogenic Orocutaneous Fistula: Diagnosis and Management-Review for Dentists

Shmakhi Sharifah Hussain A (1) , Mahdi Zahran Mohammed A (1) , Tahreer Mohammed Naser Hefzy (2) , Alhazmi Amnah Ahmed (1) , Fadiyah Nasser Alharbi (3) , Layla Ahmad Awaji (4) , Fatimah Mohammed Nasir Alhazmi (5) , Afaf Murajjiha Almutairi (6) , Haya Soud Elenazi (6) , Reem Mohammed Kinani (7) , Salih Mohammed S Aljasem (8) , Mudaher Habeb Ali Alhamoud (8)
(1) Jazan Health Cluster,Ministry of Health, Saudi Arabia,
(2) Primary Care center in Aldabeah,Ministry of Health, Saudi Arabia,
(3) Ministry Of Health, Saudi Arabia,
(4) Jazan Specialized Dental Center,Ministry of Health, Saudi Arabia,
(5) Specialized Dental Center,Ministry of Health, Saudi Arabia,
(6) Riyadh Specialized Dental Center,Ministry of Health, Saudi Arabia,
(7) Jazan Dental Center,Ministry of Health, Saudi Arabia,
(8) Al-Ahsa Health Cluster,Ministry of Health, Saudi Arabia

Abstract

Background: Odontogenic orocutaneous fistula (OCF) is an uncommon pathological communication between the oral cavity and skin, often misdiagnosed due to its atypical presentation. Chronic dental infections are the predominant cause, though trauma, osteomyelitis, medication-related osteonecrosis, and neoplasia also contribute.


Aim: To review the etiology, diagnostic challenges, and management strategies for odontogenic OCF, emphasizing its clinical significance for dental practitioners.


Methods: A comprehensive literature review was conducted, analyzing epidemiology, pathophysiology, diagnostic modalities, and treatment approaches. Key studies and case reports were synthesized to highlight common pitfalls and best practices.


Results: Odontogenic sources account for most OCF cases, typically arising from untreated pulpal necrosis and periapical infection. Misdiagnosis is frequent, with lesions often mistaken for dermatologic conditions such as cysts or granulomas. Radiographic tracing with gutta-percha and pulp vitality testing are essential for accurate localization. Endodontic therapy or extraction of the causative tooth leads to spontaneous closure in most cases, while adjunctive measures like vacuum-assisted closure may be required for complex defects. Prognosis is excellent when timely dental intervention occurs, though residual scarring may persist.


Conclusion: Early recognition of odontogenic origin is critical to prevent unnecessary interventions and aesthetic complications. Interdisciplinary collaboration between dermatology, surgery, and dentistry enhances diagnostic accuracy and patient outcomes.

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Authors

Shmakhi Sharifah Hussain A
Wedooo1430@hotmail.com (Primary Contact)
Mahdi Zahran Mohammed A
Tahreer Mohammed Naser Hefzy
Alhazmi Amnah Ahmed
Fadiyah Nasser Alharbi
Layla Ahmad Awaji
Fatimah Mohammed Nasir Alhazmi
Afaf Murajjiha Almutairi
Haya Soud Elenazi
Reem Mohammed Kinani
Salih Mohammed S Aljasem
Mudaher Habeb Ali Alhamoud
Hussain A, S. S., Mahdi Zahran Mohammed A, Tahreer Mohammed Naser Hefzy, Alhazmi Amnah Ahmed, Fadiyah Nasser Alharbi, Layla Ahmad Awaji, … Mudaher Habeb Ali Alhamoud. (2025). Odontogenic Orocutaneous Fistula: Diagnosis and Management-Review for Dentists. Saudi Journal of Medicine and Public Health, 2(2), 2460–2469. https://doi.org/10.64483/202522421

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