Integrating Genomics and Digital Health in Precision Nursing: A Narrative Review of Lab-Genetic Data Integration, EHR Systems, and Nurse-Led Lifestyle Interventions for Chronic Disease Management
Abstract
Background: The rising global burden of chronic diseases necessitates a shift from reactive, one-size-fits-all care to proactive, personalized management. Precision health, underpinned by genomic data and digital health technologies, offers a transformative pathway. However, the integration of complex genetic laboratory data into routine clinical workflow, particularly within nursing practice, remains a significant challenge. Aim: This narrative review synthesizes contemporary evidence (2010-2024) on the integration of pharmacogenomic and nutrigenomic data into Electronic Health Records (EHRs) and explores its application in guiding precision nursing interventions for chronic disease management. Methods: A systematic search of PubMed, CINAHL, Scopus, and Web of Science was conducted. Literature on genomic-EHR integration, nursing roles in genomics, digital health tools, and chronic care outcomes was thematically analyzed. Results: Evidence reveals that interoperable genomic data within EHRs, coupled with clinical decision support (CDS), can effectively guide nurse-led interventions in medication safety, dietary coaching, and lifestyle modification. Successful models highlight the nurse’s pivotal role as an interpreter, educator, and care coordinator. Key barriers include data interoperability issues, nursing genomic competency gaps, and ethical concerns. Conclusion: The convergence of genomics and health informatics creates a powerful foundation for precision nursing. Realizing its potential requires robust genomic-EHR integration, targeted education to expand nursing genomic competency, and the development of standardized, ethics-guided protocols for implementing genetically-informed care plans.
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References
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Authors
Copyright (c) 2024 Madhwi Ali Saud, Farjah Mohammed Albathali, Alanood Thalab Salman Aldafery, Nura Ghadeer M Aldhfeeri, Eidah Mohammed Alanazi, Jalal Shiwaihed Muter Aljamili, Mohammed Ahmad Mohammed Alhaj, Ibrahim Ahmed Abdo Maashi, Hassan Mohammed Abdullah Al-Omari, Mohammed Talal Ahmed Al Refaei, Ali Abdulhadi Muhaiter Al-Shammari, Wansa Raja Awad Alshammri, Muteb Salmen Sadon Almutaire
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