Laboratory-Nursing Partnerships in Managing Multi-Drug-Resistant Organisms (MDROs): A Comprehensive Review

Abdulkarim Hamad Al Atiyyah; Dalela Magna Al Mutairi; Khaleel Ibraheem Al Johani; Mohammed Burayk Al Mutairi; Hadyl Shalan Al Abdaly; Imtenan Abdullah Albreak; Meshal Abdullah Altoriqi; Wasmiya Ayad Alrasheedi

doi:10.64483/jmph-73

Authors

Abdulkarim Hamad Al Atiyyah Kingdom of Saudi Arabia , King khaled General hospital Majmaah
Dalela Magna Al Mutairi Kingdom of Saudi Arabia,King khaled General hospital Majmaah
Khaleel Ibraheem Al Johani Kingdom of Saudi Arabia,King khaled General hospital Majmaah
Mohammed Burayk Al Mutairi Kingdom of Saudi Arabia,King khaled General hospital Majmaah
Hadyl Shalan Al Abdaly Kingdom of Saudi Arabia,King khaled General hospital Majmaah
Imtenan Abdullah Albreak Kingdom of Saudi Arabia, King khaled General hospital Majmaah
Meshal Abdullah Altoriqi Kingdom of Saudi Arabia,Zulfi General Hospital
Wasmiya Ayad Alrasheedi Kingdom of Saudi Arabia,King khaled General hospital Majmaah

DOI:

https://doi.org/10.64483/jmph-73

Keywords:

MDROs, laboratory-nursing partnerships, infection control, antimicrobial resistance, surveillance

Abstract

Background: Multi-drug resistant organisms (MDROs) pose a significant threat to global healthcare, causing prolonged hospitalizations, increased mortality, and substantial economic burdens. Effective management requires robust laboratory-nursing partnerships to enhance detection and infection control.
Aim: This review evaluates the efficacy of laboratory-nursing collaborations in managing MDROs, identifies best practices, and highlights opportunities for improvement in diverse healthcare settings.
Methods: A comprehensive literature review was conducted, synthesizing studies from 2010–2025 on MDRO epidemiology, diagnostic techniques, infection control practices, and interdisciplinary strategies. Data from the CDC, WHO, and peer-reviewed journals were analyzed to assess the impact of laboratory-nursing synergies.
Results: Laboratory professionals utilize advanced diagnostics like PCR and MALDI-TOF MS for rapid MDRO identification, while nurses implement contact precautions and decolonization protocols, reducing transmission by up to 40%. Interdisciplinary communication, standardized protocols, and regional collaboratives, such as SHIELD-OC, have decreased MDRO prevalence by 30.4% in long-term care facilities. Challenges include resource constraints and variable protocol adherence.
Conclusions: Laboratory-nursing partnerships are critical for effective MDRO management. Standardizing protocols, leveraging technology, and fostering regional collaboration can enhance outcomes. Future research should explore cost-effective technologies like whole-genome sequencing and AI-based predictive models.

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