Cardiopulmonary Bypass in Nursing Practice: Clinical Management, Patient Safety, and Perioperative Care

Abdulmajeed Jahaz Alahmadi (1), Salman Fahad Alsharif (2), Norah Saad Almutairi (3), Sarah Hussain Kaabi (4), Bashayer Abdullah Alghamdi (5), Mohammed Abualqasem Ali Alameer (6), Abdul Wahab Muhammad Sahqi (6), Mashael Khallaf Qweaan Aldhafeeri (7), Afrah Muzil Noman Aldhafeeri (8), Rahmah Saleh Alfaras (9), Mada Saleh Alfaras (3), Mohammad Yahaya Thabet Mahdi (10)
(1) Al Haram Hospital, Al Madinah Al Munawwarah,Ministry of Health, Saudi Arabia,
(2) Long Term Hospital, Al Baha,Ministry of Health, Saudi Arabia,
(3) Maternity and Children’s Hospital,Ministry of Health, Saudi Arabia,
(4) Almuzahmiyah Primary Health Care (PHC),Ministry of Health, Saudi Arabia,
(5) Al-Suwaidi West Primary Health Care (PHC),Ministry of Health, Saudi Arabia,
(6) Abu Arish General Hospital,Ministry of Health, Saudi Arabia,
(7) Hafar Al-Batin Central Hospital, Ministry of Health, Saudi Arabia,
(8) Al Baldiya Primary Health Care,Ministry of Health, Saudi Arabia,
(9) Cardiac Center, King Abdulaziz Specialist Hospital,Ministry of Health, Saudi Arabia,
(10) Sabia General Hospital,Ministry of Health, Saudi Arabia

Abstract

Background: Cardiopulmonary bypass (CPB) enables complex intracardiac surgery by temporarily substituting heart and lung function with an extracorporeal circuit, creating a motionless, blood-reduced field while maintaining systemic perfusion and oxygenation. Its benefits are counterbalanced by inflammatory activation, coagulopathy, and multisystem risks that demand meticulous perioperative management.


Aim: To outline CPB fundamentals and translate them into nursing practice—detailing clinical indications, equipment and roles, preparation, intraoperative technique, complications, and team-based strategies to enhance patient safety and outcomes.


Methods: Narrative synthesis of CPB physiology and workflow across the perioperative continuum, integrating device functions (pump, oxygenator, heat exchanger, reservoirs, cannulas, filters), anticoagulation protocols, cannulation strategies (central/peripheral; one-stage/two-stage; cavoatrial/bicaval), myocardial protection (antegrade/retrograde/ostial cardioplegia), and structured team roles.


Results: Effective CPB hinges on: (1) risk-informed patient selection; (2) standardized preparation (ACT targets, heparin resistance pathways); (3) precise cannulation and de-airing; (4) tightly controlled temperature, perfusion pressures, and blood chemistry; (5) vigilant nursing surveillance for bleeding, vasoplegia, neurologic, renal, and respiratory complications; and (6) disciplined, closed-loop communication among surgeons, anesthesiologists, perfusionists, nurses, and ICU teams.


Conclusion: CPB remains indispensable for coronary, valvular, congenital, and complex aortic surgery. Nursing practice is central to safety—operationalizing protocols, recognizing early deterioration, coordinating interventions, and ensuring error-resistant handoffs. Interprofessional standardization and continuous monitoring mitigate CPB’s physiologic burdens, translating technical capability into improved recovery trajectories.

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Authors

Abdulmajeed Jahaz Alahmadi
abdulamjeeda@moh.gov.sa (Primary Contact)
Salman Fahad Alsharif
Norah Saad Almutairi
Sarah Hussain Kaabi
Bashayer Abdullah Alghamdi
Mohammed Abualqasem Ali Alameer
Abdul Wahab Muhammad Sahqi
Mashael Khallaf Qweaan Aldhafeeri
Afrah Muzil Noman Aldhafeeri
Rahmah Saleh Alfaras
Mada Saleh Alfaras
Mohammad Yahaya Thabet Mahdi
Alahmadi, A. J., Salman Fahad Alsharif, Norah Saad Almutairi, Sarah Hussain Kaabi, Bashayer Abdullah Alghamdi, Mohammed Abualqasem Ali Alameer, … Mohammad Yahaya Thabet Mahdi. (2025). Cardiopulmonary Bypass in Nursing Practice: Clinical Management, Patient Safety, and Perioperative Care. Saudi Journal of Medicine and Public Health, 2(2), 2269–2289. https://doi.org/10.64483/202522392

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